Research Associate II - Integrative Genomics Core

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

We are seeking a highly motivated Research Assistant II to join the Integrative Genomics Core. You will support a wide range of genomics workflows, including next-generation sequencing (NGS) library preparation, nucleic acid extraction, and quality control processes.

The Integrative Genomics Core provides comprehensive genomics services to support cutting-edge biomedical research. Leveraging advanced platforms such as Illumina, PacBio, Nanopore, and 10x Genomics, the core enables a broad range of genomic and epigenomic applications. These technologies empower investigators to explore complex biological systems, from cancer genomics to translational and precision medicine studies, within a highly collaborative, service-oriented environment.

As a successful candidate, you will:

· Perform DNA and RNA extraction, quantification, and quality control

· Prepare libraries for next-generation sequencing using Illumina, PacBio (SMRT sequencing), and 10x Genomics platforms

· Execute high-throughput workflows with attention to consistency and quality

· Track samples and metadata using laboratory information management systems FileMaker

· Maintain accurate and detailed laboratory records in accordance with core facility standards

· Assist in method development, optimization, and validation of new genomics workflows under supervision of core scientists

· Communicate effectively with core scientists regarding sample requirements, project status, and results

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

We are seeking a highly motivated Research Assistant II to join the Integrative Genomics Core. You will support a wide range of genomics workflows, including next-generation sequencing (NGS) library preparation, nucleic acid extraction, and quality control processes.

The Integrative Genomics Core provides comprehensive genomics services to support cutting-edge biomedical research. Leveraging advanced platforms such as Illumina, PacBio, Nanopore, and 10x Genomics, the core enables a broad range of genomic and epigenomic applications. These technologies empower investigators to explore complex biological systems, from cancer genomics to translational and precision medicine studies, within a highly collaborative, service-oriented environment.

As a successful candidate, you will:

· Perform DNA and RNA extraction, quantification, and quality control

· Prepare libraries for next-generation sequencing using Illumina, PacBio (SMRT sequencing), and 10x Genomics platforms

· Execute high-throughput workflows with attention to consistency and quality

· Track samples and metadata using laboratory information management systems FileMaker

· Maintain accurate and detailed laboratory records in accordance with core facility standards

· Assist in method development, optimization, and validation of new genomics workflows under supervision of core scientists

· Communicate effectively with core scientists regarding sample requirements, project status, and results

Your qualifications should include:

· Bachelor’s degree in molecular biology, Genetics, or related field. Master’s degree preferred.

· 2+ years of related experience in molecular biology or genomics with a Bachelor’s degree or 1+ year related experience with a Master’s degree.

· Experience with standard molecular biology techniques (PCR, qPCR, nucleic acid handling)

· 2+ years of Direct experience with next-generation sequencing library preparation is preferred

· Familiarity with Illumina sequencing platforms.

· Experience with long-read sequencing (PacBio) and/or single-cell or spatial genomics workflows (10x Genomics)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

Your qualifications should include:

· Bachelor’s degree in molecular biology, Genetics, or related field. Master’s degree preferred.

· 2+ years of related experience in molecular biology or genomics with a Bachelor’s degree or 1+ year related experience with a Master’s degree.

· Experience with standard molecular biology techniques (PCR, qPCR, nucleic acid handling)

· 2+ years of Direct experience with next-generation sequencing library preparation is preferred

· Familiarity with Illumina sequencing platforms.

· Experience with long-read sequencing (PacBio) and/or single-cell or spatial genomics workflows (10x Genomics)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.